Read the whole explanation.
The Companion connects mechanisms and clinical reasoning. The Final Stretch brings the essentials back by system and discipline.
Try cardiac rapid review →Read → understand → recall
A textbook you can
think with.
Follow a cellular mechanism, explore molecular tools, or test your cardiac physiology. Start with three open previews from our two books.
The Companion
Narrative explanations that connect mechanisms, clinical reasoning, and exam traps.
The Final Stretch
Concise review by system and discipline, with recall checkpoints for the final weeks.
Three illustrations · Interactive PCR counter · Recall checks · No sign-in
The Companion · Chapter 159Reading the Genome
Three different starting points · No sign-in
Stay for a chapter.
Room to think
A workspace for the way
you actually study.
Use the larger screen for a chapter, a mechanism, or a focused question session. The app keeps the study tools within reach.
Put the idea to work.
Practice questions, inspect explanations, and use mechanism maps to connect cause and effect.
Open the study workspace →Make time for recall.
Review flashcards with spaced repetition and revisit your Error Notebook. Use audio when reading doesn’t fit the moment.
Continue in the web app →PRACTICE / MCQs
Follow the reasoning.
Work through a clinical question, then compare your answer with the explanation. On a larger screen, the question and reasoning sit side by side.
Try MCQ practice →
RECALL / FLASHCARDS
Think. Reveal. Remember.
Recall the answer before turning the card. Open the supporting details, then rate how well you remembered it to guide your next review.
Start a flashcard session →Read the card
Question: Non-smoker in their 40s with early-onset emphysema and basilar-predominant bullous changes on CXR — diagnosis?
Answer: Alpha-1-antitrypsin (AAT) deficiency.
Your desk is the starting point.
The mobile app brings the same study library to shorter sessions away from your computer. Web is the main workspace; mobile keeps it close.
One library. More ways to learn.
ReadTwo study books
PracticeClinical questions
RecallSpaced repetition
ConnectMechanism maps
RevisitError Notebook
ListenAudio lessons
How You'll Study
01MCQ PracticeWork through the clinical reasoning
Practice clinical questions, then review the explanation and the reasoning behind each answer. Filter your study session to focus on the material you want to work on.
02FlashcardsReturn to ideas over time
Choose a deck, reveal an answer, and rate your recall. Spaced repetition schedules future reviews using your responses; daily limits help keep the workload manageable.
03Clinical PearlsBring the key point back into focus
Review concise clinical teaching points alongside the broader explanations in your study library.
04Mechanism MapsFollow the chain from cause to effect
Explore explanations that connect physiology, disease, and treatment. Use the mechanism library to revisit the steps behind a clinical finding.
05Exam BlocksPractice working against the clock
Start a timed question block, flag items to revisit, and review your results after submitting. Use it to practice pacing and identify material to return to.
06The Final StretchA focused second pass
Browse the rapid-review book by system and discipline. Read concise explanations and use inline recall checkpoints to bring the essentials back.
07Audio LessonsTake an explanation with you
Listen to narrated lessons from the audio library. Adjust playback speed and use available transcripts to follow the material at your own pace.
08Voice StudyPractice explaining an idea out loud
Use the app’s voice study mode to talk through material with an AI partner. It uses your microphone and may save transcripts. Check explanations against source material. How voice study works.
09Error NotebookTurn a missed question into a return visit
Revisit missed questions and their explanations in a dedicated notebook. Pin entries you want to return to and keep difficult concepts within reach.
10Best Next SessionA clear place to start
Open the next-session tool when you want help choosing what to study. Review your study activity and progress, then continue with a focused session.
11The CompanionMake room for the full explanation
Read the narrative textbook in the web or mobile app. Explore three free previews across both books, with explanatory diagrams and recall checks you can try without signing in.
AI that helps you study the mechanism
Read an explanation, listen to a lesson, then practice explaining it out loud. How MedRune uses AI ↗
Supports regular recall
Spaced repetition uses your review ratings to schedule flashcards
Connects explanations
Explore mechanisms, drugs, and pathways through connected study material
Shows your study activity
Review your activity and progress to help choose what to revisit
AI-narrated lessons
Narrated lessons in the audio library for commutes, walks, or downtime
Physician-Led
AI-assisted authoring with physician-led editorial review, editable content, and review tools for editors
A physician’s perspective on studying medicine
MedRune was founded by Omer Alavna, MD, to help students understand difficult mechanisms, practice applying them, and revisit what they forget. His background in medicine and software development shapes how the study experience is built.
Start on the web
Open the web app to sign in or create an account. For a mobile beta invitation, leave your email below.
You’re on the list. We’ll email you about mobile access as invitations become available.
We use your email for mobile-access updates. Privacy · Unsubscribe or get help
Prefer to see pricing first? View plans →